Pain：针灸可有效预防痉挛复发和加重

摄影记者从日前在京召集的2011年医书国际研讨会上获悉，首都医科大学附属北京中医医院医书一个中心经医学研究证实，传统的中医医书疗法可必需预防癫痫的复发和延重。系统性研究期刊昨日撰写在国际享有盛誉病理学期刊《疼痛》上，成为中国大陆首篇撰写于该杂志的医学研究期刊。该文还被国际出名病理学生态学管理机构 Faculty of 1000 medicine（千名病理学家）收录于。

据了解，作为医学常见病之一，癫痫生育率高，且危害不堪重负。目前，必先18岁~65岁人群的癫痫患病率高达9.3%，且有逐年升高态势。医书病患头痛在中国已经有数千年的历史文化。北京中医医院医书一个中心自2004年另设头痛专家门诊，开展了基于“菱角王北关”、国医大师贺普仁等多位享有盛誉医书学家治痛方面的头痛研究。

据该一个中心主任王麟鹏介绍，该项目实行单盲、双仿真、结果表明的形式，在国际上5家医院的医书科共招募140名无先兆癫痫病患者，随机分为四组，分别为病患四组（医书延安慰剂）和大鼠（假针延氟桂利嗪）。四组病患者每周医书病患3次，每晚口服药物。结果显示，4紧接著，病患四组癫痫的必需缓解率为59%，大鼠为40%；病患四组疼痛整年平均上升4.1天，大鼠平均上升1.9天。16紧接著，病患四组必需缓解率为56%，大鼠为37%；病患四组疼痛整年平均上升 4.1天，大鼠平均上升2天。

研究人员据此认为，医书可以作为癫痫的预防复发和延重的方法，其治果也远胜此前国外的系统性研究。由于其研究方法的大胆和更为重要，该期刊还被国际出名病理学生态学管理机构“千名科学家”收录于。（生物谷 Bioon.com）

doi:10.1016/j.pain.2011.04.006PMC:PMID:

Efficacy of acupuncture for migraine prophylaxis: A single-blinded, double-dummy, randomized controlled trial

Lin-Peng Wang,Xiao-Zhe Zhang,Jia Guo,Hui-Lin Liu,Yan Zhang,Cun-Zhi Liu,Jing-Hong Yi,Li-Ping Wang,Ji-Ping Zhao,Shan-Shan Li

Summary This multicenter, double-dummy trial suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks. Abstract Insufficient clinical trial data were ailable to prove the efficacy of acupuncture for migraine prophylaxis. A multicenter, double-dummy, single-blinded, randomized controlled clinical trial was conducted at the outpatient departments of acupuncture at 5 hospitals in China to evaluate the effectiveness of acupuncture. A total of 140 patients with migraine without aura were recruited and assigned randomly to 2 different groups: the acupuncture group treated with verum acupuncture plus placebo and the control group treated with sham acupuncture plus flunarizine. Treated by acupuncture 3 times per week and drugs every night, patients from both groups were evaluated at week 0 (baseline), week 4, and week 16. The primary outcome was measured by the proportion of responders (defined as the proportion of patients with a reduction of migraine days by at least 50%). The secondary outcome measures included the number of migraine days, visual ogue scale (VAS, 0 to 10cm) for pain, as well as the physical and mental component summary scores of the 36-item short-form health survey (SF-36). The patients in the acupuncture group had better responder rates and fewer migraine days compared with the control group (P.05). The results suggested that acupuncture was more effective than flunarizine in decreasing days of migraine attacks, whereas no significantly differences were found between acupuncture and flunarizine in reduction of pain intensity and improvement of the quality of life.